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This study was undertaken to evaluate the effect of the expression level of thymidylate synthase (TS) gene in colon carcinoma tissue on the response to 5-fluorouracil (5-FU) therapy. METHODS AND MATERIALS: Surgically resected specimens from 93 patients with stage II or III colon carcinoma were examined for the expression of TS gene by reverse transcription polymerase chain reaction analysis. The pathological response to 5-FU therapy was evaluated by postoperative examination of tumor tissues. Tumors with a reduction rate of the TS mRNA expression in 5-FU-treated samples of > or = 30% were defined as having a good response. The frequency of the good response in the TS-high expression group was significantly higher than that in the TS-low expression group, with a difference in the survival of patients of 28 months. TS expression level in colon carcinoma tissue may be used to predict the response to 5-FU therapy.Field of the Invention
The present invention relates to an operation portion of a touch panel.
Description of the Background Art
There is a known touch panel mounted on a display such as a liquid crystal display device. For example, such a touch
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Early diagnosis of breast cancer is important to reduce mortality rates of the disease. Identification of microcalcifications in mammograms can be a diagnostic tool, but the false-positive identification has a large impact in the preoperative diagnosis. This study proposes a method to detect microcalcifications automatically and a computer-aided detection (CAD) software. A fully automatic segmentation method for the breast region using Hough transform is proposed. For the microcalcification detection, the proposed CAD method uses an edge classification method and a pattern recognition algorithm. Experimental results on the Digital Mammography Image Database, GRID Digitised Mammograms and BI-RADS digitised mammograms, demonstrate the efficiency and robustness of the proposed system.U_{Y}^{0}-U_{Y}^{1}\right|

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